Vitamin D Supplementation and Prevention of Type 2 Diabetes.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Observational studies support an association between a low blood 25-hydroxyvitamin D level and the risk of type 2 diabetes.

However, whether vitamin D supplementation lowers the risk of diabetes is unknown.

Who Took Part

The age groups tagged for this paper are middle-aged adults and older adults, both men and women.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

The primary outcome in this time-to-event analysis was new-onset diabetes, and the trial design was event-driven, with a target number of diabetes events of 508.

What Was Measured

Observational studies support an association between a low blood 25-hydroxyvitamin D level and the risk of type 2 diabetes.

Topics PubMed links to this paper include Cholecalciferol, Diabetes Mellitus, Type 2, Dietary Supplements, Disease-Free Survival, Kaplan-Meier Estimate, Prediabetic State and Risk Factors.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2019 (The New England journal of medicine), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.