Cardiac autonomic dysfunctions are recovered with vitamin D replacement in apparently healthy individuals with vitamin D deficiency.

What Was Tested

This observational study looks at Vitamin D, K2, Magnesium and Zinc.

The researchers aimed to evaluate the impact of VitD replacement on cardiac autonomic dysfunction.

Why It Was Studied

Vitamin D (VitD) has important prohormone functions in a wide range of clinical processes.

Although it is known that individuals with VitD deficiency have cardiac autonomic dysfunction, there are no convincing data regarding the effect of VitD replacement.

Who Took Part

The abstract describes 50 subjects taking part.

By PubMed's age tags, the people studied were adults, both men and women.

Fifty-two apparently healthy subjects with VitD deficiency and 50 healthy control subjects were enrolled.

Prior to VitD replacement, 24-hr Holter recordings were obtained, and HRV parameters were recorded.

How the Study Was Run

VitD levels were measured 2 months later after replacement, and control 24-hr Holter recordings were analyzed.

What Was Measured

The subject headings attached to it are Autonomic Nervous System, Cohort Studies, Electrocardiography, Electrocardiography, Ambulatory, Vitamin D and Vitamin D Deficiency.

The authors tagged it with the keywords cardiac autonomic dysfunction and heart rate variability.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 50 subjects.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2019 (Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.