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Effects of zinc supplementation on serum adiponectin concentration and glycemic control in patients with type 2 diabetes.
Plain-language guide to PMID 31345359 (2019): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 60 patients.
Key Facts
- PMID
- 31345359
- Journal
- Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
- Year
- 2019
- Study type
- Randomized Controlled Trial
- Authors
- Asghari S et al. (5 authors)
- DOI
- 10.1016/j.jtemb.2019.05.007
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
The aim of this study was to investigate the effect of zinc supplementation on glycemic control, and the potential mediating role of adiponectin, in patients with type 2 diabetes.
Why It Was Studied
Adiponectin is a well-known adipokine with anti-diabetic, anti-atherogenic, and anti-inflammatory properties.
Who Took Part
The study group was 60 patients.
PubMed indexes the participants as adults and middle-aged adults, both men and women.
How the Study Was Run
In design terms this was a randomized, double-blind and placebo-controlled study.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
Neither the patients nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
Some patients received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
Circulating levels of adiponectin, zinc, glucose homeostasis parameters, and lipid profiles, as well as anthropometric parameters and dietary intakes, were assessed.
What Was Measured
Topics PubMed links to this paper include Adiponectin, Blood Glucose, Diabetes Mellitus, Type 2, Dietary Supplements, Gluconates, Insulin Resistance and Lipids.
Author keywords: Zinc.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 60 patients.
Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2019 (Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)), a journal based in Germany.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.