Delayed versus immediate oxytocin infusion after amniotomy for induction of labour: A randomised controlled pilot trial

What Was Tested

This randomized controlled trial paper looks at Oxytocin.

To get a preliminary understanding of the amniotomy-to-delivery interval, patients' experiences and risks by awaiting spontaneous contractions after amniotomy and to explore the need and feasibility for a larger randomised controlled trial.

Who Took Part

The age groups tagged for this paper are adults, women only.

Women with term, singleton pregnancy in vertex position undergoing labour induction for one of the five following indications: prolonged pregnancy, mild hypertensive disorders, diabetes, expected macrosomia, maternal request, were randomised to amniotomy with 12-hours delayed oxytocin (DO), or amniotomy with immediate oxytocin (IO).

How the Study Was Run

The researchers set it up as a randomized and pilot study.

Because people in this Oxytocin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

It is described as a pilot, a small early test of whether a larger Oxytocin study would be practical.

The researchers performed a randomised controlled pilot trial in a peripheral teaching hospital in Amsterdam, The Netherlands.

What Was Measured

PubMed files the paper under topics including Amniotomy, Labor, Induced, Oxytocics, Oxytocin and Pilot Projects.

Author keywords: Induction, Labour and Perception.

What This Means in Plain Language

The paper is a randomized and pilot study of Oxytocin.

Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2019 (European journal of obstetrics, gynecology, and reproductive biology), a journal based in Ireland.

More context: the Oxytocin compound page, all human trials.