Effects of dietary intervention on vitamin B12 status and cognitive level of 18-month-old toddlers in high-poverty areas: a cluster-randomized controlled trial.

What Was Tested

Researchers studied Cyanocobalamin (Vitamin B12) in this randomized controlled trial publication.

The aims of this study were to explore the vitamin B12 status of toddlers living in high-poverty areas of China and to observe the effects of different complementary foods on the vitamin B12 status and cognitive level of these toddlers.

Why It Was Studied

The local diet in high-poverty areas in China is mainly vegetarian, and children may be more vulnerable to vitamin B12 deficiency.

The larger trial in which this study was nested was registered at clinical trials.gov as NCT00726102.

Who Took Part

By PubMed's age tags, the people studied were infants, both men and women.

At 18 months, a subsample of the 180 toddlers (60 from each group) was randomly tested for serum vitamin B12 and total homocysteine (tHcy) levels, and their neurodevelopment was evaluated.

How the Study Was Run

The researchers set it up as a randomized study.

The participants were allocated by chance, so the Cyanocobalamin (Vitamin B12) group and the comparison group should start out alike.

What Was Measured

The subject headings attached to it are Anemia, Child Development, China, Cognition, Diet, Edible Grain and Food, Fortified.

Author keywords: Complementary food, Deficiency, Neurodevelopment, Toddler and Vitamin B12.

What This Means in Plain Language

The paper is a randomized study of Cyanocobalamin (Vitamin B12).

Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2019 (BMC pediatrics), a journal based in England.

More context: the Cyanocobalamin (Vitamin B12) compound page, all human trials.