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Effects of flaxseed and flaxseed oil supplement on serum levels of inflammatory markers, metabolic parameters and severity of disease in patients with ulcerative colitis.

Plain-language guide to PMID 31519285 (2019): open-label randomized controlled trial of Copper (Supplement) in 90 patients.

Key Facts

PMID
31519285
Journal
Complementary therapies in medicine
Year
2019
Study type
Randomized Controlled Trial
Authors
Morshedzadeh N et al. (9 authors)
DOI
10.1016/j.ctim.2019.07.012

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Copper (Supplement), published as a randomized controlled trial.

The present study aimed to evaluate the possible effect of grounded flaxseed and flaxseed oil on serum levels of inflammatory markers, metabolic parameters, and the severity of disease in patients with UC.

Who Took Part

According to the abstract, 90 patients were involved.

The age groups tagged for this paper are adults, both men and women.

The weight, waist circumference, systolic and diastolic blood pressure, serum inflammatory markers (interleukin-6 (IL-6), interferon gamma (INF-γ), transforming growth factor beta (TGF-β), and Erythrocyte Sedimentation Rate (ESR)), and fecal calprotectin were measured at the baseline and end of the study.

How the Study Was Run

The researchers set it up as a randomized and open-label study.

Random assignment meant chance, not the researchers, decided who got Copper (Supplement) and who got the comparison, which limits bias.

Nothing was hidden in this open-label Copper (Supplement) study: the patients and staff both knew the treatment.

What Was Measured

PubMed files the paper under topics including Biomarkers, Blood Pressure, Colitis, Ulcerative, Dietary Supplements, Flax, Inflammation and Inflammation Mediators.

Author keywords: Flaxseed, Flaxseed oil, Inflammatory bowel disease, Severity and Ulcerative colitis.

What This Means in Plain Language

The paper is a randomized and open-label study of Copper (Supplement) in 90 patients.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2019 (Complementary therapies in medicine), a journal based in Scotland.

More context: the Copper (Supplement) compound page, all human trials.

Our Notes on the Compound

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.