Effects of high-dose vitamin D supplementation on the occurrence of post-operative atrial fibrillation after coronary artery bypass grafting: randomized controlled trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Who Took Part

By PubMed's age tags, the people studied were middle-aged adults and older adults, both men and women.

Patients were divided into those who received oral vitamin D (treatment group; n = 58) and those who did not (control group; n = 58) 48 h before CABG surgery.

Patients were followed up during hospitalisation process with respect to POAF.

How the Study Was Run

In design terms this was a randomized, single-blind and parallel-group study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Only one side, usually the participants, was kept unaware of whether Vitamin D, K2, Magnesium and Zinc was given.

Groups ran in parallel: each of the participants stayed in one arm throughout.

The study was a randomized controlled, blinded and parallel-arm trial conducted on 116 who had vitamin D deficiency or insufficiency during the pre-operative evaluation were included in the study conducted between January 2018 and January 2019.

What Was Measured

PubMed files the paper under topics including Atrial Fibrillation, Coronary Artery Bypass, Coronary Artery Disease, Dietary Supplements, Postoperative Complications, Postoperative Period and Vitamin D.

The authors tagged it with the keywords Coronary artery bypass grafting, Post-operative atrial fibrillation and Vitamin D supplementation.

What This Means in Plain Language

The paper is a randomized, single-blind and parallel-group study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2020 (General thoracic and cardiovascular surgery), a journal based in Japan.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.