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Intake of whey isolate supplement and muscle mass gains in young healthy adults when combined with resistance training: a blinded randomized clinical trial (pilot study).

Plain-language guide to PMID 31565912 (2020): double-blind randomized controlled trial of Copper (Supplement), muscle gain, sarcopenia & building muscle after 40.

Key Facts

PMID
31565912
Journal
The Journal of sports medicine and physical fitness
Year
2020
Study type
Randomized Controlled Trial
Authors
Duarte NM et al. (4 authors)
DOI
10.23736/S0022-4707.19.09741-X

What This Study Did, in Plain Language

What Was Tested

Researchers studied Copper (Supplement) in the context of muscle gain, sarcopenia & building muscle after 40 in this randomized controlled trial publication.

Muscle strength was assessed using an isokinetic protocol at angular velocities of 60º.s-1 (5 repetitions) and 180º.s-1 (10 repetitions) with a range of motion of 0º to 100º on a dynamometer to determine peak torque (PT).

Why It Was Studied

Because of its rich branched chain amino acids content, namely leucine, whey appears to favor muscle protein synthesis through the mTOR pathway in combination with resistance training, when taken after exercise in sufficient amounts.

Who Took Part

The age groups tagged for this paper are teenagers, young adults and adults, both men and women.

In the present study resistance trained (≥3 months) participants (men and women) between the age of 18 and 30 years old were randomized in a blinded fashion to whey protein isolate (N.=4) and an isocaloric placebo (N.=4) groups.

Lean body mass (LBM) and body fat percentage (%BF) were assessed using a body composition analyzer through segmental multi-frequency bioelectrical impedance method.

How the Study Was Run

The researchers set it up as a randomized, double-blind, placebo-controlled and pilot study.

The participants were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.

Blinding on both sides kept the participants and researchers unaware of who received Copper (Supplement).

A placebo (an inactive look-alike) gave the Copper (Supplement) group a baseline to be compared against.

It is described as a pilot, a small early test of whether a larger Copper (Supplement) study would be practical.

All variables were assessed before and after interventions.

What Was Measured

Topics PubMed links to this paper include Body Composition, Dietary Supplements, Muscle Strength, Muscle, Skeletal, Pilot Projects, Resistance Training and Torque.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement) in people with muscle gain, sarcopenia & building muscle after 40.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2020 (The Journal of sports medicine and physical fitness), a journal based in Italy.

More context: the Copper (Supplement) compound page, Muscle gain, sarcopenia & building muscle after 40 research.

Our Notes on the Compound

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.