Vitamin D as a Biomarker of Ill Health among the Over-50s: A Systematic Review of Cohort Studies.

What It Covers

Researchers studied Vitamin D, K2, Magnesium and Zinc in this systematic review publication.

The association between circulating levels of vitamin D and the incidence of chronic diseases is known.

The identification of vitamin D as a biomarker of physiological/pathological ageing could contribute to expanding current knowledge of its involvement in healthy ageing.

Who the Included Studies Covered

The age groups tagged for this paper are middle-aged adults, both men and women.

According to PRISMA guidelines, a systematic review was conducted on cohorts studying the role of 25OH-Vitamin D [25(OH)D] and 1,25(OH)2-Vitamin D [1,25(OH)2D] concentrations as biomarkers of healthy ageing.

The researchers consulted MedLine, Scopus, and Web of Science to search for studies on the association between vitamin D status in populations of originally healthy adults, and outcomes of longevity, illness, and physical and cognitive functionality.

How the Review Was Done

The quality of the studies was assessed using the Newcastle Ottawa scale.

What Was Measured

The association between circulating levels of vitamin D and the incidence of chronic diseases is known.

PubMed files the paper under topics including Age Factors, Aging, Biomarkers, Cause of Death, Health Status, Health Status Indicators and Prognosis.

Author keywords: cohorts, healthy ageing and vitamin D.

What This Means in Plain Language

This is a systematic review of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2019 (Nutrients), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.