Combined nicotine patch with gum versus nicotine patch alone in smoking cessation in Hong Kong primary care clinics: a randomised controlled trial

What Was Tested

This randomized controlled trial paper looks at Therapeutic nicotine (patch, non-peptide).

NCT03836560 from ClinicalTrial.gov , 9 Feb 2019.

Who Took Part

PubMed indexes the participants as adults and middle-aged adults, both men and women.

How the Study Was Run

In design terms this was a randomized and parallel-group study.

Random assignment meant chance, not the researchers, decided who got Therapeutic nicotine (patch, non-peptide) and who got the comparison, which limits bias.

Groups ran in parallel: each of the participants stayed in one arm throughout.

This is a one-year, two-arm, parallel randomised trial.

Five hundred sixty smokers, who smoked ≥10 cigarettes/day for ≥1 year, were randomized to combined and single NRT.

Combined NRT group received counseling and nicotine patch & gum.

Single NRT group received counselling and nicotine patch.

Primary outcome was abstinence rate measured as self-reported 7-day point prevalence with CO validated at 52 weeks.

What Was Measured

Secondary outcomes included smoking abstinence rates at 4, 12, & 26 weeks.

The subject headings attached to it are Chewing Gum, Combined Modality Therapy, Hong Kong, Primary Health Care, Smoking Cessation and Tobacco Use Cessation Devices.

Author keywords: Combined nicotine replacement therapy, Effectiveness, Nicotine patch and Randomised controlled trial.

What This Means in Plain Language

The paper is a randomized and parallel-group study of Therapeutic nicotine (patch, non-peptide).

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2019 (BMC public health), a journal based in England.

More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.