One week of magnesium supplementation lowers IL-6, muscle soreness and increases post-exercise blood glucose in response to downhill running.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a clinical trial.

Magnesium supplementation modulates glucose metabolism and inflammation, which could influence exercise performance and recovery.

This study investigated the effect of magnesium intake on physiological responses and performance during eccentric exercise and recovery.

Who Took Part

The age groups tagged for this paper are adults, men only.

How the Study Was Run

In design terms this was a double-blind, placebo-controlled and crossover study.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

Each person switched between Vitamin D, K2, Magnesium and Zinc and the comparison at some point, usually with a gap in between.

Nine male recreational runners completed a counterbalanced, double-blind, placebo-controlled, cross-over study, registered at ClinicalTrial.gov.

At baseline and 24 h post-TT, maximal muscle force was measured.

Interleukin-6 (IL-6), soluble interleukin-6 receptor (sIL-6R) and creatine kinase (CK) were measured at rest, 0 h, 1 h and 24 h post-TT.

Muscle soreness was measured at the previous times plus 48 h and 72 h post.

Glucose and lactate were measured during the TT.

What Was Measured

Topics PubMed links to this paper include Blood Glucose, Creatine Kinase, Dietary Supplements, Exercise, Inflammation, Interleukin-6 and Magnesium.

Author keywords: Muscle soreness and Recovery.

What This Means in Plain Language

The paper is a double-blind, placebo-controlled and crossover study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2019 (European journal of applied physiology), a journal based in Germany.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.