← Human Trials & Peer-Reviewed Studies

A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study.

Plain-language guide to PMID 31627309 (2019): randomized controlled trial of Copper (Supplement) in 72 women.

Key Facts

PMID
31627309
Journal
Nutrients
Year
2019
Study type
Randomized Controlled Trial
Authors
Bolke L et al. (4 authors)
DOI
10.3390/nu11102494

What This Study Did, in Plain Language

What Was Tested

Researchers studied Copper (Supplement) in this randomized controlled trial publication.

The purpose of this randomized, placebo-controlled, blind study was to investigate the effects of the drinkable nutraceutical ELASTEN® (QUIRIS Healthcare, Gütersloh, Germany) on skin aging and skin health.

A skin assessment was carried out and based on objective validated methods, including corneometry (skin hydration), cutometry (elasticity), the use of silicon skin replicas with optical 3D phase-shift rapid in-vivo measurements (PRIMOS) (roughness), and skin sonography (density).

The verum group was followed for an additional four weeks (without intake of the test product) to evaluate the sustainability of the changes induced by the intake of the test product.

Why It Was Studied

This controlled interventional trial was performed on 72 healthy women aged 35 years or older.

Who Took Part

The abstract describes 72 women taking part.

The age groups tagged for this paper are adults, middle-aged adults and older adults, women only.

How the Study Was Run

In design terms this was a randomized and placebo-controlled study.

The women were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.

Some women received a placebo instead of Copper (Supplement), giving a reference point.

What Was Measured

The subject headings attached to it are Collagen, Dietary Supplements, Skin, Skin Aging and Surveys and Questionnaires.

Author keywords: beauty, bioavailability, collagen peptides, corneometry, cutometry and high coverage [HC] collagen complex.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Copper (Supplement) in 72 women.

The publication is from 2019 (Nutrients), a journal based in Switzerland.

More context: the Copper (Supplement) compound page, all human trials.

Our Notes on the Compound

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.