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Effects of Zinc Supplementation on Nutritional Status in Children with Chronic Kidney Disease: A Randomized Trial.
Plain-language guide to PMID 31694220 (2019): multicenter randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 31694220
- Journal
- Nutrients
- Year
- 2019
- Study type
- Randomized Controlled Trial
- Authors
- Escobedo-Monge MF et al. (7 authors)
- DOI
- 10.3390/nu11112671
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
The positive or negative change in patients' body mass index (BMI) Z-score, serum albumin, zinc and C-reactive protein (CRP) levels were used to evaluate the effect of ZS.
Why It Was Studied
Zinc is an essential micronutrient for human beings and its deficiency affects their normal growth and development.
Who Took Part
PubMed indexes the participants as infants, young children, children and teenagers, both men and women.
A randomized-trial multicentric study was conducted in 48 CKD (23 females) patients under 18-years-old, for a year.
Anthropometric measurements and biochemical analysis were performed.
How the Study Was Run
The researchers set it up as a randomized and multicenter study.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Running at several centres spread the Vitamin D, K2, Magnesium and Zinc study over different clinics and patient groups.
Hypozincemia was determined by serum zinc concentration (SZC) using atomic absorption spectrophotometry.
What Was Measured
The subject headings attached to it are Body Mass Index, C-Reactive Protein, Dietary Supplements, Hypoalbuminemia, Micronutrients, Nutritional Status and Peru.
Author keywords: chronic kidney disease, hypozincemia, serum albumin, serum zinc concentration, stunted growth and undernutrition.
What This Means in Plain Language
The paper is a randomized and multicenter study of Vitamin D, K2, Magnesium and Zinc.
The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2019 (Nutrients), a journal based in Switzerland.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.