← Human Trials & Peer-Reviewed Studies

Effects of Vitamin D and Calcium Fortified Yogurts on Gait, Cognitive Performances, and Serum 25-Hydroxyvitamin D Concentrations in Older Community-Dwelling Females: Results from the GAit, MEmory, Dietary and Vitamin D (GAME-D2) Randomized Controlled Trial.

Plain-language guide to PMID 31779179 (2019): single-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 20 participants.

Key Facts

PMID
31779179
Journal
Nutrients
Year
2019
Study type
Randomized Controlled Trial
Authors
Beauchet O et al. (8 authors)
DOI
10.3390/nu11122880

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The aim of this randomized controlled trial (RCT) was to examine the effects of vitamin D and calcium fortified yogurt on spatiotemporal gait parameters, cognitive performance, handgrip strength, and serum 25OHD levels in healthy older females.

Who Took Part

The abstract describes 20 participants taking part.

By PubMed's age tags, the people studied were older adults, women only.

Cognitive performances, including global cognitive functioning assessed with the Mini Mental Status Examination (MMSE) were recorded.

How the Study Was Run

The researchers set it up as a randomized, single-blind and parallel-group study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Only one side, usually the participants, was kept unaware of whether Vitamin D, K2, Magnesium and Zinc was given.

The Vitamin D, K2, Magnesium and Zinc group and the comparison group ran side by side rather than switching.

Spatiotemporal gait parameters (mean value and coefficient of variation) were assessed using a computerized walkway.

Handgrip strength was measured with hydraulic dynamometers.

All the outcomes were assessed at baseline and at the end of follow-up.

The primary outcome was the coefficient of variation of stride time.

What Was Measured

The subject headings attached to it are Calcium, Cognition, Gait, Vitamin D and Yogurt.

The authors tagged it with the keywords hypovitaminosis D, older adults and randomized controlled trial.

What This Means in Plain Language

The paper is a randomized, single-blind and parallel-group study of Vitamin D, K2, Magnesium and Zinc in 20 participants.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2019 (Nutrients), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.