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Vitamin D assessment in perioperative medicine and critical care : A prospective observational pilot study.
Plain-language guide to PMID 31802221 (2021): pilot observational study of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 31802221
- Journal
- Wiener klinische Wochenschrift
- Year
- 2021
- Study type
- Observational Study
- Authors
- Zajic P et al. (8 authors)
- DOI
- 10.1007/s00508-019-01584-x
What This Study Did, in Plain Language
What Was Tested
This observational study looks at Vitamin D, K2, Magnesium and Zinc.
This study was carried out to assess the influence of perioperative fluid loading on 25-hydroxy-vitamin D [25(OH)D] levels.
Why It Was Studied
There is controversy about the impact of acute illness on vitamin D levels.
The study evaluated the clinical utility of a commonly available chemiluminescence assay (ECLIA, IDS-iSYS) and liquid chromatography/mass spectrometry (LC-MS/MS) in the diagnosis of vitamin D deficiency in this setting.
Who Took Part
PubMed indexes the participants as adults.
In this prospective observational pilot study in adult patients undergoing cardiovascular surgery on cardiopulmonary bypass (CPB), blood samples drawn at preoperative baseline (t1), after weaning from CPB (t2), on intensive care unit (ICU) admission (t3) and on the first (t4) and second (t5) postoperative days were analyzed.
How the Study Was Run
The design is described as pilot.
It is described as a pilot, a small early test of whether a larger Vitamin D, K2, Magnesium and Zinc study would be practical.
What Was Measured
There is controversy about the impact of acute illness on vitamin D levels.
The study evaluated the clinical utility of a commonly available chemiluminescence assay (ECLIA, IDS-iSYS) and liquid chromatography/mass spectrometry (LC-MS/MS) in the diagnosis of vitamin D deficiency in this setting.
Topics PubMed links to this paper include Chromatography, Liquid, Critical Care, Perioperative Medicine, Pilot Projects, Tandem Mass Spectrometry and Vitamin D.
The authors tagged it with the keywords Diagnosis and Vitamin D deficiency.
What This Means in Plain Language
The paper is a pilot study of Vitamin D, K2, Magnesium and Zinc.
Results are reported in around 8 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2021 (Wiener klinische Wochenschrift), a journal based in Austria.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.