The influence of vitamin D supplementation on IGF-1 levels in humans: A systematic review and meta-analysis.

What It Covers

This meta-analysis looks at IGF-1 LR3 and Vitamin D, K2, Magnesium and Zinc.

To address these inconsistencies, this study was conducted to determine the impact of vitamin D supplementation on IGF-1 levels through a systematic review and meta-analysis of randomized controlled trials (RCTs).

Why It Was Studied

Inconsistencies exist with regard to influence of vitamin D supplementation on IGF-1 levels.

Who the Included Studies Covered

By PubMed's age tags, the people studied were children, adults, middle-aged adults and older adults, both men and women.

How the Review Was Done

A comprehensive systematic search was carried out in PubMed/MEDLINE, Web of Science, SCOPUS and Embase for RCTs that investigated the impact of vitamin D intake on circulating IGF-1 levels from inception until June 2019.

Subgroup analysis was performed to specify the source of heterogeneity among studies.

What Was Measured

Inconsistencies exist with regard to influence of vitamin D supplementation on IGF-1 levels.

Topics PubMed links to this paper include Dietary Supplements, Insulin-Like Growth Factor I, Randomized Controlled Trials as Topic, Vitamin D and Vitamins.

The authors tagged it with the keywords 25-Hydroxyvitamin D and IGF-1.

What This Means in Plain Language

This is a meta-analysis of IGF-1 LR3 and Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2020 (Ageing research reviews), a journal based in England.

More context: the IGF-1 LR3 compound page and the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.