The effect of vitamin D supplementation on hemoglobin concentration: a systematic review and meta-analysis.

What It Covers

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a meta-analysis.

The purpose of this review was to investigate the effect of vitamin D supplements on hemoglobin concentration in subjects aged 17.5-68 years old; using randomized controlled trials (RCTs).

Who the Included Studies Covered

The age groups tagged for this paper are teenagers, young adults, adults, middle-aged adults and older adults, both men and women.

The studies were reviewed systematically, and quality assessments were evaluated by the guidelines of the Cochrane risk of bias.

The effect of vitamin D supplements (n = 14) on hemoglobin concentration was considered as primary outcome, while its effects on the levels of ferritin, transferrin saturation and iron status were derived as secondary outcomes.

How the Review Was Done

Relevant RCT studies were identified from January 2000 to January 2019 by using MeSH terms in PubMed, Embase, Cochrane Library, Clinical trials, Scopus databases and gray literature.

In total, 1385 subjects with age range of 17.5 to 68 years old were examined for 3 h to 6 months; Mean (standard deviation) or median interquartile changes in the hemoglobin concentration in each treatment group was recorded for meta-analysis.

What Was Measured

Topics PubMed links to this paper include Dietary Supplements, Ferritins, Hemoglobins, Randomized Controlled Trials as Topic, Vitamin D and Vitamins.

Author keywords: Anemia, Iron status and RCT.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2020 (Nutrition journal), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.