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A Dermonutrient Containing Special Collagen Peptides Improves Skin Structure and Function: A Randomized, Placebo-Controlled, Triple-Blind Trial Using Confocal Laser Scanning Microscopy on the Cosmetic Effects and Tolerance of a Drinkable Collagen Supplement.
Plain-language guide to PMID 32017646 (2020): double-blind randomized controlled trial of Copper (Supplement) in 60 volunteers.
Key Facts
- PMID
- 32017646
- Journal
- Journal of medicinal food
- Year
- 2020
- Study type
- Randomized Controlled Trial
- Authors
- Laing S et al. (4 authors)
- DOI
- 10.1089/jmf.2019.0197
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Copper (Supplement), published as a randomized controlled trial.
The purpose of this randomized, placebo-controlled, triple-blind trial on 60 healthy female volunteers was to assess the cosmetic effects on skin quality of a food supplement containing special collagen peptides together with acerola extract, vitamin C, vitamin E, biotin, and zinc after an intake of 12 weeks (Elasten®, QUIRIS Healthcare, Germany).
Why It Was Studied
The expert grader assessing the confocal laser scanning microscopy images was additionally blinded regarding the time when the image was taken (on days 1 or 85).
Who Took Part
The study group was 60 volunteers.
PubMed indexes the participants as middle-aged adults, women only.
How the Study Was Run
In design terms this was a randomized, double-blind and placebo-controlled study.
The volunteers were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.
Neither the volunteers nor the staff measuring them knew who was on Copper (Supplement), so expectations could not easily colour the readings.
A placebo (an inactive look-alike) gave the Copper (Supplement) group a baseline to be compared against.
What Was Measured
The expert grader assessing the confocal laser scanning microscopy images was additionally blinded regarding the time when the image was taken (on days 1 or 85).
PubMed files the paper under topics including Collagen, Dietary Supplements, Microscopy, Confocal, Skin, Skin Aging and Vitamins.
The authors tagged it with the keywords antiaging, collagen peptides, dermal collagen structure, dermonutrient, oral collagen supplement and skin beauty.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement) in 60 volunteers.
The publication is from 2020 (Journal of medicinal food), a journal based in United States.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.