The effects of concurrent training order on body composition and serum concentrations of follistatin, myostatin and GDF11 in sarcopenic elderly men.

What Was Tested

Researchers studied Follistatin-344 in this randomized controlled trial publication.

Due to the important role of follistatin (FLST), myostatin (MSTN) and growth differentiation factor 11 (GDF11) in muscle mass regulation; alterations in the FLST to MSTN ratio (F:M) may result in muscle mass changes in response to different concurrent training (CT) order.

This study investigated the influence of 8 weeks of CT order on body composition and serum concentrations of FLST, MSTN, their ratio (F:M) and GDF11 in sarcopenic elderly men.

Who Took Part

The age groups tagged for this paper are middle-aged adults and older adults, men only.

Thirty sarcopenic elderly men (age = 64.3 ± 3.5 years) were randomly assigned into one of three groups, endurance followed by resistance training (E + R; n = 10), resistance followed by endurance training (R + E; n = 10) or control (C; n = 10).

How the Study Was Run

The design is described as randomized.

The participants were allocated by chance, so the Follistatin-344 group and the comparison group should start out alike.

What Was Measured

PubMed files the paper under topics including Body Composition, Bone Morphogenetic Proteins, Follistatin, Growth Differentiation Factors, Muscle Strength, Muscle, Skeletal and Myostatin.

The authors tagged it with the keywords Elderly, Endurance training, Resistance training and Sarcopenic.

What This Means in Plain Language

The paper is a randomized study of Follistatin-344.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2020 (Experimental gerontology), a journal based in England.

More context: the Follistatin-344 compound page, all human trials.