Association of serum 25-OH vitamin D₃ with serum IgE and the Pediatric Asthma Severity Score in patients with pediatric asthma.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Objective: The aim of this study was to evaluate the relationship among the vitamin D₃ status, Pediatric Asthma Severity Score (PASS), and inflammatory indicators of pediatric asthma.

Why It Was Studied

Methods: Among all of the pediatric patients with asthma and with asthma exacerbation, 100 patients were randomly enrolled in the study and subdivided into three groups according to serum levels of 25-OH vitamin D₃.

The control group consisted of 100 sex- and age-matched healthy subjects.

Who Took Part

The study group was 100 patients.

The age groups tagged for this paper are young children, children and teenagers, both men and women.

The count of the white blood cells, eosinophil count, and serum levels of total immunoglobulin E (IgE) plus 25-OH vitamin D₃ were measured in all the subjects.

How the Study Was Run

The design is described as randomized.

The patients were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Asthma exacerbation severity was evaluated based on the PASS before starting the medical care.

What Was Measured

Methods: Among all of the pediatric patients with asthma and with asthma exacerbation, 100 patients were randomly enrolled in the study and subdivided into three groups according to serum levels of 25-OH vitamin D₃.

The subject headings attached to it are Asthma, Calcifediol, Case-Control Studies, Disease Progression, Immunoglobulin E, Iran and Prevalence.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 100 patients.

The publication is from 2020 (Allergy and asthma proceedings), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.