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of vitamin D does not reduce resting Blood Pressure and Inhibit Post-Exercise Hypotension in elderly women: a pilot study.

Plain-language guide to PMID 32187256 (2020): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 11 women, low blood pressure and orthostatic hypotension.

Key Facts

PMID
32187256
Journal
Anais da Academia Brasileira de Ciencias
Year
2020
Study type
Randomized Controlled Trial
Authors
Gonçalves MDCR et al. (10 authors)
DOI
10.1590/0001-3765202020190227

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in the context of low blood pressure and orthostatic hypotension in this randomized controlled trial publication.

On day 7, the subjects performed 30 minutes of aerobic exercise with blood pressure measurement before exercise and every 10 minutes after exercise during 60 minutes, besides cardiac autonomic modulation.

Who Took Part

The abstract describes 11 women taking part.

PubMed indexes the participants as older adults, women only.

How the Study Was Run

The design is described as randomized, double-blind, placebo-controlled and pilot.

The women were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

Some women received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

It is described as a pilot, a small early test of whether a larger Vitamin D, K2, Magnesium and Zinc study would be practical.

What Was Measured

On day 7, the subjects performed 30 minutes of aerobic exercise with blood pressure measurement before exercise and every 10 minutes after exercise during 60 minutes, besides cardiac autonomic modulation.

The subject headings attached to it are Autonomic Nervous System, Blood Pressure, Pilot Projects, Post-Exercise Hypotension, Vitamin D and Vitamin D Deficiency.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 11 women in people with low blood pressure and orthostatic hypotension.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The publication is from 2020 (Anais da Academia Brasileira de Ciencias), a journal based in Brazil.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Low blood pressure and orthostatic hypotension research.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.