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[Effectiveness of magnesium sulfate compared to rocuronium for rapid sequence tracheal intubation in adults: clinical randomized trial].
Plain-language guide to PMID 32199656 (2020): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 68 patients.
Key Facts
- PMID
- 32199656
- Journal
- Brazilian journal of anesthesiology (Elsevier)
- Year
- 2020
- Study type
- Randomized Controlled Trial
- Authors
- Barbosa FT et al. (6 authors)
- DOI
- 10.1016/j.bjan.2019.12.002
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
Magnesium sulphate has been used in anesthesia because it has relevant clinical features such as: analgesia, autonomic response control and muscle relaxation.
Using the agent to establish adequate conditions for tracheal intubation remains controversial.
Who Took Part
According to the abstract, 68 patients were involved.
By PubMed's age tags, the people studied were teenagers, young adults, adults and older adults, both men and women.
Patients were divided into two groups.
How the Study Was Run
The design is described as randomized and double-blind.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Neither the patients nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
The primary variable was the clinical status of tracheal intubation.
What Was Measured
The subject headings attached to it are Analgesics, Magnesium Sulfate, Neuromuscular Nondepolarizing Agents, Rapid Sequence Induction and Intubation and Rocuronium.
Author keywords: Anestesia geral, Apendicite, Appendicitis, Ensaio clínico randomizado, General anesthesia and Intubação orotraqueal.
What This Means in Plain Language
The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 68 patients.
Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2020 (Brazilian journal of anesthesiology (Elsevier)), a journal based in Brazil.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.