Vitamin D, calcium or a combination of vitamin D and calcium for the treatment of nutritional rickets in children.

What It Covers

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a systematic review.

Therefore, it is important to compare the effects of vitamin D, calcium or a combination of vitamin D and calcium for the treatment of nutritional rickets in children living in different settings.

To assess the effects of vitamin D, calcium or a combination of vitamin D and calcium for the treatment of nutritional rickets in children.

Why It Was Studied

Nutritional rickets is a disease which affects children, especially in low- and middle-income countries.

It causes problems such as skeletal deformities and impaired growth.

Who the Included Studies Covered

PubMed indexes the participants as infants, young children, children and teenagers.

How the Review Was Done

The researchers searched CENTRAL, MEDLINE, LILACS, WHO ICTRP Search Portal and ClinicalTrials.gov.

The date of the last search of all databases was 25 July 2019.

The researchers applied no language restrictions.

What Was Measured

Two review authors independently screened the title and abstracts of all studies, extracted data and assessed the risk of bias of included studies.

The researchers conducted meta-analyses for the outcomes reported by study authors.

Topics PubMed links to this paper include Calcium, Fractures, Bone, Randomized Controlled Trials as Topic, Rickets, Vitamin D, Vitamin D Deficiency and Vitamins.

What This Means in Plain Language

This is a systematic review of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 23 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2020 (The Cochrane database of systematic reviews), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.