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The effects of vitamin D and curcuminoids supplementation on anthropometric measurements and blood pressure in type 2 diabetic patients with coexisting hypovitaminosis D: A double-blind, placebo-controlled randomized clinical trial.

Plain-language guide to PMID 32359741 (2020): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc, low blood pressure and orthostatic hypotension.

Key Facts

PMID
32359741
Journal
Clinical nutrition ESPEN
Year
2020
Study type
Randomized Controlled Trial
Authors
Ebrahimkhani S et al. (3 authors)
DOI
10.1016/j.clnesp.2020.02.017

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc in the context of low blood pressure and orthostatic hypotension.

This study was performed to evaluate the effects of curcuminoids and vitamin D, simultaneously or singly on anthropometric measurements and blood pressure in T2DM patients with insufficient vitamin D level.

Who Took Part

Blood pressure and anthropometric measurements were evaluated before and after intervention.

How the Study Was Run

In design terms this was a randomized and placebo-controlled study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

What Was Measured

PubMed files the paper under topics including Blood Pressure, Diabetes Mellitus, Type 2, Diarylheptanoids, Dietary Supplements, Vitamin D and Vitamin D Deficiency.

The authors tagged it with the keywords Anthropometric measurements, Curcuminoids and Type 2 diabetes.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in people with low blood pressure and orthostatic hypotension.

Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2020 (Clinical nutrition ESPEN), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Low blood pressure and orthostatic hypotension research.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.