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Zinc Oxide Inhibits Axillary Colonization by Members of the Genus Corynebacterium and Attenuates Self-perceived Malodour: A Randomized, Double-blind, Placebo-controlled Trial.
Plain-language guide to PMID 32399578 (2020): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 30 volunteers.
Key Facts
- PMID
- 32399578
- Journal
- Acta dermato-venereologica
- Year
- 2020
- Study type
- Randomized Controlled Trial
- Authors
- Ågren MS et al. (9 authors)
- DOI
- 10.2340/00015555-3499
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
The aim of this study was to determine the effects of zinc oxide on the axillary microbiota, odour and pH in a randomized, double-blind, placebo-controlled trial in 30 healthy volunteers.
Why It Was Studied
Malodour from the axilla is commonly caused by specific microbes, and may be inhibited by zinc oxide.
The microbiota and pH were analysed before and during treatment.
Who Took Part
The abstract describes 30 volunteers taking part.
By PubMed's age tags, the people studied were young adults and adults, both men and women.
How the Study Was Run
In design terms this was a randomized, double-blind and placebo-controlled study.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.
Some volunteers received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
What Was Measured
Topics PubMed links to this paper include Anti-Bacterial Agents, Axilla, Corynebacterium, Denmark, Hydrogen-Ion Concentration, Microbial Viability and Odorants.
Author keywords: malodour, skin pH, susceptibility tests, topical antiseptics and microbiota.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 30 volunteers.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
The publication is from 2020 (Acta dermato-venereologica), a journal based in Sweden.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.