Antimicrobial Photodynamic Therapy with Diode laser and Methylene blue as an adjunct to scaling and root planning: A clinical trial

What Was Tested

The paper reports a study of Methylene blue (non-peptide stack partner), published as a clinical trial.

The aim of this study was to evaluate the effect of aPDT with 660 nm diode laser and methylene blue as an adjunct to scaling and root planning (SRP) on clinical periodontal parameters.

Why It Was Studied

Chronic periodontitis, the most common periodontal disease, is the destruction of tooth supporting structures and alveolar bone which may result in teeth exfoliation.

Who Took Part

In this clinical trial, the researchers assessed aPDT as an adjunct to scaling and root planning (SRP) in chronic periodontitis treatment.

A total of 50 subjected were enrolled.

How the Study Was Run

The case group received SRP and aPDT with methylene blue solution as photosensitizer and diode laser (wavelength= 660 nm, power = 150 mW) irradiation.

The control group received only SRP.

The effect on clinical parameters, namely Plaque index (PI), Gingival index (GI), and probing depth (PD) was recorded at baseline, 6 weeks, 3 months and 6 months.

What Was Measured

The subject headings attached to it are Anti-Bacterial Agents, Anti-Infective Agents, Chronic Periodontitis, Combined Modality Therapy, Dental Scaling, Lasers, Semiconductor and Methylene Blue.

Author keywords: ., Antimicrobial photodynamic therapy, Clinical trial and Scaling and root planing.

What This Means in Plain Language

This is a clinical trial of Methylene blue (non-peptide stack partner).

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2020 (Photodiagnosis and photodynamic therapy), a journal based in Netherlands.

More context: the Methylene blue (non-peptide stack partner) compound page, all human trials.