Effect of calcitriol combined with sevelamer carbonate on serum parathyroid hormone in patients with chronic renal failure

What Was Tested

The paper reports a study of Parathyroid Hormone (PTH 1-84), published as a randomized controlled trial.

This study aimed to observe and analyze the effect of calcitriol combined with sevelamer carbonate on serum parathyroid hormone in patients with chronic renal failure.

The patients were randomly divided into two groups: a research group and a control group, each containing 90 cases.

Who Took Part

According to the abstract, 180 patients were involved.

PubMed indexes the participants as middle-aged adults and older adults, both men and women.

This study included 180 patients who had been treated for chronic renal failure in their hospital were enrolled as research objects.

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Parathyroid Hormone (PTH 1-84) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The research group was treated with calcitriol combined with sevelamer carbonate, and the control group was treated with calcitriol alone.

What Was Measured

Topics PubMed links to this paper include Alkaline Phosphatase, Biomarkers, Calcitriol, Cholesterol, LDL, Creatinine, Kidney Failure, Chronic and Parathyroid Hormone.

The authors tagged it with the keywords Chronic renal failure, Serum parathyroid hormone. and Sevelamer carbonate.

What This Means in Plain Language

The paper is a randomized study of Parathyroid Hormone (PTH 1-84) in 180 patients.

The publication is from 2020 (Cellular and molecular biology (Noisy-le-Grand, France)), a journal based in France.

More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.