Effect of orally administered magnesium on postoperative pain level and trismus after surgical removal of the lower third molars: a randomized, double-blind, placebo-controlled trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc in the context of post-surgical inflammation and surgery recovery, published as a randomized controlled trial.

Pain and trismus are the most common postoperative complications following a surgical removal of the lower third molar.

This randomized, double-blind, placebo-controlled clinical trial evaluated the effect of orally administrated magnesium on postoperative pain and trismus after surgical removal of the lower third molars.

Why It Was Studied

This study is registered on http:clinicaltrials.gov under protocol no.

Who Took Part

The abstract describes 80 participants taking part.

The study was conducted on 80 participants who were divided into two groups.

Participants in both groups had their two lower molars surgically removed.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

Each group took different oral forms of magnesium citrate.

For one randomly selected third molar, participants received either magnesium citrate tablets or lozenges.

For the surgical removal of the lower third molar of the opposite side, the participants received either placebo tablets or lozenges.

This manuscript was written in accordance with the Consort recommendation.

What Was Measured

Topics PubMed links to this paper include Edema, Magnesium, Molar, Third, Postoperative Pain, Tooth Extraction, Tooth, Impacted and Trismus.

The authors tagged it with the keywords Magnesium citrate, Surgical removal of third molar and Third molar.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 80 participants in people with post-surgical inflammation and surgery recovery.

Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2020 (Clinical oral investigations), a journal based in Germany.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Post-surgical inflammation and surgery recovery research.