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Vitamin D levels in IBD: a randomised trial of weight-based versus fixed dose vitamin D supplementation.

Plain-language guide to PMID 32538182 (2020): open-label randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 173 patients.

Key Facts

PMID
32538182
Journal
Scandinavian journal of gastroenterology
Year
2020
Study type
Randomized Controlled Trial
Authors
Kojecky V et al. (8 authors)
DOI
10.1080/00365521.2020.1774921

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Objectives: Body weight is one of the factors affecting blood levels of 25-hydroxyvitamin D (25OHD).

The primary outcome measure was 25OHD level after a follow-up period.Results: A total of 173 patients were analysed.

Who Took Part

The study group was 173 patients.

By PubMed's age tags, the people studied were adults and middle-aged adults, both men and women.

How the Study Was Run

The researchers set it up as a randomized and open-label study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Everyone knew when Vitamin D, K2, Magnesium and Zinc was being given (open label), which is simpler to run but leaves more room for expectations to affect what is reported.

What Was Measured

Objectives: Body weight is one of the factors affecting blood levels of 25-hydroxyvitamin D (25OHD).

The primary outcome measure was 25OHD level after a follow-up period.Results: A total of 173 patients were analysed.

The subject headings attached to it are Cholecalciferol, Czech Republic, Inflammatory Bowel Diseases, Logistic Models, Multivariate Analysis, Vitamin D and Vitamin D Deficiency.

The authors tagged it with the keywords body weight, dietary supplements and vitamin D intake.

What This Means in Plain Language

The paper is a randomized and open-label study of Vitamin D, K2, Magnesium and Zinc in 173 patients.

The publication is from 2020 (Scandinavian journal of gastroenterology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.