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The effect of moderate-intensity aerobic training on pulmonary function and estrogen receptor-alpha gene in postmenopausal women with vitamin D deficiency: A randomized control trial.

Plain-language guide to PMID 32739460 (2020): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
32739460
Journal
Respiratory physiology & neurobiology
Year
2020
Study type
Randomized Controlled Trial
Authors
Malandish A et al. (5 authors)
DOI
10.1016/j.resp.2020.103510

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The purpose of this study was to examine the effect of 12 weeks of moderate-intensity aerobic training on pulmonary function, ERα gene expression, serum levels of sex hormones and Vit D in PMW with Vit D deficiency.

Why It Was Studied

The impact of aerobic training on pulmonary function by modulating gene expression of estrogen receptor-alpha (ERα), sex hormones and 25-hydroxy vitamin D (Vit D) in postmenopausal women (PMW) with Vit D deficiency is uncertain.

Who Took Part

The age groups tagged for this paper are middle-aged adults and older adults, women only.

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Twenty-nine sedentary PMW with Vit D deficiency (aged 45-65 yrs) were randomized to exercise (EX, n = 15) and control (C, n = 14) groups.

The pulmonary function parameters, ERα gene expression, serum levels of sex hormones and Vit D were measured at baseline and week-12.

What Was Measured

The subject headings attached to it are Cardiorespiratory Fitness, Estradiol, Estrogen Receptor alpha, Exercise, Exercise Therapy, Outcome Assessment, Health Care and Postmenopause.

Author keywords: Exercise intervention, Pulmonary function and Vitamin D deficiency.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 2 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2020 (Respiratory physiology & neurobiology), a journal based in Netherlands.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.