Serum vitamin D, vitamin D binding protein levels and leukocyte vitamin D receptor gene expression in patients with ischaemic stroke.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

To investigate the possible contributions of serum 25 hydroxyvitamin D and vitamin D binding protein levels along with leukocyte vitamin D receptor gene expression in patients with ischaemic stroke.

Who Took Part

According to the abstract, 2017, patients were involved.

PubMed indexes the participants as adults, middle-aged adults and older adults.

The randomised controlled single-blind study was conducted at the Mayo Hospital, Lahore, Pakistan, from September 2015 to September 2017, and comprised patients aged 40-75 years with Arbeitsgemeinschaft für Osteosynthesefragen type A2 and A3 per trochanteric fracture.

The patients randomised into two equal groups.

How the Study Was Run

The researchers set it up as a randomized and single-blind study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Only one side, usually the patients, was kept unaware of whether Vitamin D, K2, Magnesium and Zinc was given.

Follow-up was done at 2nd, 6th and 12th weeks, and at 6th, 9th and 12th month post-operatively.

Variables evaluated were frequency of union, surgical time, approximate amount of blood loss and complications.

The functional assessment was done by using Harris hip score.

SPSS 20 was used for data analysis.

What Was Measured

PubMed files the paper under topics including Brain Ischemia, Gene Expression, Hip Fractures, Ischemic Stroke, Leukocytes, Pakistan and Receptors, Calcitriol.

Author keywords: Ischemic stroke, Vitamin D, Vitamin D binding protein, Gene expression, Correlation.

What This Means in Plain Language

The paper is a randomized and single-blind study of Vitamin D, K2, Magnesium and Zinc in 2017, patients.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2020 (JPMA. The Journal of the Pakistan Medical Association), a journal based in Pakistan.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.