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Vitamin D3 supplementation improves glycemic control in type 2 diabetic patients: Results from an Italian clinical trial.
Plain-language guide to PMID 32795167 (2022): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 2 patients.
Key Facts
- PMID
- 32795167
- Journal
- International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
- Year
- 2022
- Study type
- Randomized Controlled Trial
- Authors
- Derosa G et al. (7 authors)
- DOI
- 10.1024/0300-9831/a000673
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
Background: to evaluate the effects of Vitamin D3 on glyco-metabolic control in type 2 diabetic patients with Vitamin D deficiency.
Why It Was Studied
The researchers evaluated anthropometric parameters, glyco-metabolic control, and parathormone (PTH) value at baseline, after 3, and 6 months.
Who Took Part
According to the abstract, 2 patients were involved.
Methods: one hundred and seventeen patients were randomized to placebo and 122 patients to Vitamin D3.
How the Study Was Run
The researchers set it up as a randomized and placebo-controlled study.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.
What Was Measured
The researchers evaluated anthropometric parameters, glyco-metabolic control, and parathormone (PTH) value at baseline, after 3, and 6 months.
Topics PubMed links to this paper include Blood Glucose, Cholecalciferol, Diabetes Mellitus, Type 2, Dietary Supplements, Glycated Hemoglobin, Glycemic Control and Hypoglycemic Agents.
The authors tagged it with the keywords Vitamin D deficiency, supplementation and type 2 diabetes mellitus.
What This Means in Plain Language
The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 2 patients.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
The publication is from 2022 (International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition), a journal based in Singapore.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.