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Effect of oxytocin infusion on reducing blood loss during abdominal myomectomy: A randomized controlled trial

Plain-language guide to PMID 32810088 (2020): single-blind randomized controlled trial study of Oxytocin in 2018, women.

Key Facts

PMID
32810088
Journal
JPMA. The Journal of the Pakistan Medical Association
Year
2020
Study type
Randomized Controlled Trial
Authors
Ahmed M et al. (4 authors)
DOI
10.5455/JPMA.14026

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Oxytocin, published as a randomized controlled trial.

Who Took Part

The study group was 2018, women.

The age groups tagged for this paper are adults, women only.

The single-blind randomised control trial was conducted at the Obstetrics and Gynaecology Department of Military Hospital, Rawalpindi, Pakistan, July 15, 2017, to January 15, 2018, and comprised women with intramural fibroids of American Society of Anaesthesia class I and II who were candidates for elective abdominal myomectomy.

The women were randomised into study and control groups.

How the Study Was Run

In design terms this was a randomized and single-blind study.

Because people in this Oxytocin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Only one side, usually the women, was kept unaware of whether Oxytocin was given.

In the control group, pure normal saline was given.

The main outcome measure was intra-operative blood loss.

Data was analysed using SPSS 21.

What Was Measured

PubMed files the paper under topics including Blood Loss, Surgical, Leiomyoma, Oxytocin, Pakistan, Uterine Myomectomy and Uterine Neoplasms.

The authors tagged it with the keywords Abdominal myomectomy, Fibroids, Intra-operative blood loss, Oxytocin..

What This Means in Plain Language

The paper is a randomized and single-blind study of Oxytocin in 2018, women.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2020 (JPMA. The Journal of the Pakistan Medical Association), a journal based in Pakistan.

More context: the Oxytocin compound page, all human trials.

Our Notes on the Compound

Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.