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Effect of diurnal intermittent fasting during Ramadan on ghrelin, leptin, melatonin, and cortisol levels among overweight and obese subjects: A prospective observational study
Plain-language guide to PMID 32845924 (2020): observational study study of Ghrelin.
Key Facts
- PMID
- 32845924
- Journal
- PloS one
- Year
- 2020
- Study type
- Observational Study
- Authors
- Al-Rawi N et al. (7 authors)
- DOI
- 10.1371/journal.pone.0237922
What This Study Did, in Plain Language
What Was Tested
Researchers studied Ghrelin in this observational study publication.
The present study aimed to examine the effect of diurnal intermittent fasting (DIF) during Ramadan on daytime levels of ghrelin, leptin, melatonin, and cortisol hormones in a group of overweight and obese subjects, and to determine how anthropometric, dietary, and lifestyle changes during the month of Ramadan correlate with these hormonal changes.
Why It Was Studied
Levels of cortisol, melatonin, ghrelin, and leptin are highly correlated with circadian rhythmicity.
The levels of these hormones are affected by sleep, feeding, and general behaviors, and fluctuate with light and dark cycles.
Who Took Part
By PubMed's age tags, the people studied were adults, both men and women.
Fifty-seven overweight and obese male (40) and female (17) subjects were enrolled in this study.
Anthropometric measurements, dietary intake, sleep duration, and hormonal levels of serum ghrelin, leptin, melatonin, and salivary cortisol were assessed one week before the start of Ramadan fasting and after 28 days of fasting at fixed times of the day (11:00 am-1:00 pm).
How the Study Was Run
A time span of 28 days appears in the methods.
What Was Measured
Levels of cortisol, melatonin, ghrelin, and leptin are highly correlated with circadian rhythmicity.
The levels of these hormones are affected by sleep, feeding, and general behaviors, and fluctuate with light and dark cycles.
The subject headings attached to it are Circadian Rhythm, Diet, Energy Intake, Fasting, Ghrelin, Hemodynamics and Hydrocortisone.
What This Means in Plain Language
This is a observational study of Ghrelin over 28 days.
Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2020 (PloS one), a journal based in United States.
More context: the Ghrelin compound page, all human trials.
Our Notes on the Compound
Ghrelin: A 28-amino-acid stomach hormone that signals hunger and triggers growth hormone release; studied in human trials as an infusion.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.