Vitamin D during pregnancy and its association with birth outcomes: a Brazilian cohort study.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a clinical study.

Evidence is lacking on how variation in vitamin D concentrations during gestation affects perinatal outcomes.

Therefore, the researchers evaluated the association between vitamin D serum concentrations during pregnancy and neonatal outcomes.

Best linear unbiased prediction of random coefficients model was used to determine the association between the mean rate of change in vitamin D during pregnancy concentrations and neonatal outcomes.

Who Took Part

The abstract describes 180 women taking part.

PubMed tags the participants as women only.

A prospective cohort of 180 healthy Brazilian pregnant women was followed and plasma 25-hydroxyvitamin [25(OH)D, nmol/L] was measured at 5-13 (baseline), 20-26 and 30-36 gestational weeks.

How the Study Was Run

Birth weight (BW), birth length (BL), BW z-scores, BL z-scores, first minute Apgar, small for gestational age (SGA), large for gestational age (LGA) and preterm birth were the outcomes.

Multiple linear and Poisson regression models were estimated.

What Was Measured

The subject headings attached to it are Birth Weight, Brazil, Cohort Studies, Gestational Age, Pregnancy Outcome, Premature Birth and Vitamin D.

What This Means in Plain Language

This is a clinical study of Vitamin D, K2, Magnesium and Zinc in 180 women.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2021 (European journal of clinical nutrition), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.