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Vitamin D supplementation in obese Sri Lankan children: a randomized controlled trial.

Plain-language guide to PMID 32891139 (2020): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
32891139
Journal
BMC pediatrics
Year
2020
Study type
Randomized Controlled Trial
Authors
Samaranayake DBDL et al. (7 authors)
DOI
10.1186/s12887-020-02329-w

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

This study aimed to determine the effect of vitamin D supplementation on obesity and related metabolic abnormalities among obese Sri Lankan children with VDD.

Why It Was Studied

Micronutrient deficiencies are identified among obese individuals.

Vitamin D deficiency (VDD) is prevalent in obese children, and is hypothesized to cause insulin resistance and metabolic abnormalities.

Who Took Part

PubMed indexes the participants as children.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

Ethics Review Committee of Faculty of Medicine, University of Colombo approved the protocol.

What Was Measured

The subject headings attached to it are Blood Glucose, Dietary Supplements, Obesity, Sri Lanka, Vitamin D and Vitamin D Deficiency.

Author keywords: Childhood obesity, Insulin resistance and Randomized controlled trial.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2020 (BMC pediatrics), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.