Effects of High-Dose Vitamin D Supplementation on Phase Angle and Physical Function in Patients with Prostate Cancer on ADT.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Bioelectrical impedance analysis (BIA)-derived phase angle may reflect frailty and functional decline in cancer patients.

Who Took Part

PubMed indexes the participants as middle-aged adults and older adults, men only.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

Phase angle was measured by BIA.

Physical function measures included handgrip strength, 6-minute walk test, Short Performance Physical Battery and leg extension.

All testing was completed at baseline, week 12 and week 24.

What Was Measured

The subject headings attached to it are Androgen Antagonists, Dietary Supplements, Hand Strength, Prostatic Neoplasms and Vitamin D.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2021 (Nutrition and cancer), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.