Effect of vitamin D supplementation versus placebo on essential hypertension in patients with vitamin D deficiency: a double-blind randomized clinical trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

This study aimed to assess the effect of vitamin D supplementation on primary hypertension.

Why It Was Studied

Findings from randomized trials addressing the effect of vitamin D supplementation and blood pressure are inconsistent and have been the subject of recent debate.

This double-blind randomized clinical trial was conducted on patients aged 26-84 years with essential hypertension from March 2017 to April 2019.

Who Took Part

According to the abstract, 208 patients were involved.

By PubMed's age tags, the people studied were adults, middle-aged adults, older adults and people over 80.

Patients with vitamin D insufficiency (serum vitamin D levels 20-30 ng/ml) or vitamin D deficiency (serum vitamin D levels <20 ng/ml) were enrolled in the study.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

The patients were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Blinding on both sides kept the patients and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Some patients received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

Systolic and diastolic blood pressure was measured before the intervention and one and two months thereafter.

What Was Measured

PubMed files the paper under topics including Blood Pressure, Dietary Supplements, Essential Hypertension, Iran, Vitamin D and Vitamin D Deficiency.

The authors tagged it with the keywords Clinical Trial.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 208 patients.

The publication is from 2020 (Journal of clinical hypertension (Greenwich, Conn.)), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.