Intravenous magnesium sulfate vs. morphine sulfate in relieving renal colic: A randomized clinical trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Renal colic emerging from renal stone is virtually the most severe pain which is experienced.

Intravenous infusion of morphine sulfate is known as a usual treatment for the disease.

Who Took Part

The abstract describes 80 patients taking part.

PubMed indexes the participants as adults and middle-aged adults, both men and women.

The researchers conducted a double-blind randomized clinical trial in renal colic patients who had referred to the emergency department of Shahid Sadoughi Hospital in Yazd, Iran.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Neither the patients nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

The primary outcome was the pain score measured on a numerical rating scale at 0, 10 and 20 minutes after infusion.

Data were analyzed using SPSS16.

What Was Measured

Topics PubMed links to this paper include Analgesics, Analgesics, Opioid, Iran, Magnesium Sulfate, Morphine, Pain Management and Pain Measurement.

Author keywords: Randomized controlled trial and Renal colic.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 80 patients.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2021 (The American journal of emergency medicine), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.