Minimally invasive parathyroidectomy guided by intraoperative parathyroid hormone monitoring (IOPTH) and preoperative imaging versus bilateral neck exploration for primary hyperparathyroidism in adults.

What It Covers

The paper reports a study of Parathyroid Hormone (PTH 1-84) in the context of hyperparathyroidism, published as a meta-analysis.

To assess the effects of minimally invasive parathyroidectomy (MIP) guided by preoperative imaging and intraoperative parathyroid hormone monitoring versus bilateral neck exploration (BNE) for the surgical management of primary hyperparathyroidism.

Why It Was Studied

Bilateral neck exploration (BNE) is the traditional approach to sporadic primary hyperparathyroidism.

With the availability of the preoperative imaging techniques and intraoperative parathyroid hormone assays, minimally invasive parathyroidectomy (MIP) is fast becoming the favoured surgical approach.

Who the Included Studies Covered

By PubMed's age tags, the people studied were adults.

How the Review Was Done

The researchers searched CENTRAL, MEDLINE, WHO ICTRP and ClinicalTrials.gov.

The date of the last search of all databases was 21 October 2019.

There were no language restrictions applied.

What Was Measured

Bilateral neck exploration (BNE) is the traditional approach to sporadic primary hyperparathyroidism.

The researchers included randomised controlled trials comparing MIP to BNE for the treatment of sporadic primary hyperparathyroidism in persons undergoing surgery for the first time.

PubMed files the paper under topics including Bias, Hyperparathyroidism, Primary, Hypocalcemia, Minimally Invasive Surgical Procedures, Monitoring, Intraoperative, Neck and Neck Dissection.

What This Means in Plain Language

This is a meta-analysis of Parathyroid Hormone (PTH 1-84) in people with hyperparathyroidism.

Its findings take up roughly 32 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2020 (The Cochrane database of systematic reviews), a journal based in England.

More context: the Parathyroid Hormone (PTH 1-84) compound page, Hyperparathyroidism research.