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Assessing the effect of nicotine dose in cigarette smoking on sleep quality.

Plain-language guide to PMID 33118055 (2021): randomized controlled trial of Therapeutic nicotine (patch, non-peptide).

Key Facts

PMID
33118055
Journal
Sleep & breathing = Schlaf & Atmung
Year
2021
Study type
Randomized Controlled Trial
Authors
AlRyalat SA et al. (7 authors)
DOI
10.1007/s11325-020-02238-3

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Therapeutic nicotine (patch, non-peptide), published as a randomized controlled trial.

This study aimed to compare higher vs lower nicotine levels in cigarette smoking on sleep quality.

Why It Was Studied

While several studies assessed the relation between cigarette smoking and sleep, there are still very few studies assessing the effect of nicotine in cigarette smoking on sleep.

Who Took Part

PubMed indexes the participants as adults and middle-aged adults, both men and women.

For each participant, the researchers included data regarding baseline and the last follow up at 6 weeks, where the researchers compared insomnia, sleep problems, and awakening at night, in addition to different depression and affect scores.

How the Study Was Run

The design is described as randomized.

Because people in this Therapeutic nicotine (patch, non-peptide) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

What Was Measured

While several studies assessed the relation between cigarette smoking and sleep, there are still very few studies assessing the effect of nicotine in cigarette smoking on sleep.

Topics PubMed links to this paper include Cigarette Smoking, Nicotine, Sleep Quality and Sleep Wake Disorders.

The authors tagged it with the keywords Cigarettes and Insomnia.

What This Means in Plain Language

The paper is a randomized study of Therapeutic nicotine (patch, non-peptide).

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2021 (Sleep & breathing = Schlaf & Atmung), a journal based in Germany.

More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.

Our Notes on the Compound

Therapeutic nicotine (patch, non-peptide): Pure nicotine as a signaling tool, separated from smoking and vaping.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.