The effect of vitamin D supplementation on the muscle damage after eccentric exercise in young men: a randomized, control trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

This study was designed to determine the modulating effect of vitamin D supplementation on the degree of muscle cell damage caused by eccentric exercise in young men.

Why It Was Studied

Vitamin D contributes to the optimal functioning of muscles.

Who Took Part

According to the abstract, 60 volunteers were involved.

The age groups tagged for this paper are young adults, men only.

60 male volunteers (20-24 years old) taking part in this study were divided in two groups - with suboptimal (S) and optimal (O;) 25(OH)D plasma levels.

These groups were randomly subdivided into groups with vitamin D supplementation (experimental: SE and OE) and controls (SC and OC).

How the Study Was Run

The design is described as randomized.

The volunteers were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

During each test, blood samples used for determination of 25(OH)D, Il-1β, myoglobin (Mb) levels and CK, LDH activity were taken at three timepoints: before the test, 1 h and 24 h after it ended.

After distribution normality testing (Saphiro-Wilk test), statistical analyses were performed.

Non-parametric: Kruskal-Wallis test and the Wilcoxon test were applied, and the Dunn-Bonferroni test as a post-hoc test.

What Was Measured

Topics PubMed links to this paper include 25-Hydroxyvitamin D 2, Body Mass Index, Calcium, Creatine Kinase, Dietary Supplements, Exercise and Exercise Test.

The authors tagged it with the keywords CK, Eccentric exercise, Il-1β, LDH, Muscle cell damage and Myoglobin.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 60 volunteers.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2020 (Journal of the International Society of Sports Nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.