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Assessing the impact of a mushroom-derived food ingredient on vitamin D levels in healthy volunteers.

Plain-language guide to PMID 33176826 (2020): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
33176826
Journal
Journal of the International Society of Sports Nutrition
Year
2020
Study type
Randomized Controlled Trial
Authors
Pinto JM et al. (5 authors)
DOI
10.1186/s12970-020-00387-0

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The aim of this study was to assess the impact of a mushroom-derived food ingredient on vitamin D status in recreationally active, healthy volunteers.

Why It Was Studied

Prevalence of vitamin D insufficiency/deficiency has been noted in athletic populations, although less is known about recreationally active individuals.

Who Took Part

By PubMed's age tags, the people studied were adults.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

Venous blood samples were collected at baseline, week 6 and 12 for analysis of serum 25(OH)D2 and 25(OH)D3 using liquid chromatography mass spectrometry.

Habitual dietary intake and activity were monitored across the intervention.

What Was Measured

Topics PubMed links to this paper include 25-Hydroxyvitamin D 2, Agaricales, Calcifediol, Cholecalciferol, Diet, Ergocalciferols and Food, Fortified.

Author keywords: Recreationally active, UV radiated mushrooms, Vitamin D status and Vitamin D2.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2020 (Journal of the International Society of Sports Nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.