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Effect of magnesium supplementation on emergence delirium and postoperative pain in children undergoing strabismus surgery: a prospective randomised controlled study.

Plain-language guide to PMID 33208099 (2020): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 66 children.

Key Facts

PMID
33208099
Journal
BMC anesthesiology
Year
2020
Study type
Randomized Controlled Trial
Authors
Lee JH et al. (7 authors)
DOI
10.1186/s12871-020-01192-7
Registered trial
NCT03132701

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Prospectively registered May 8, 2017.

Who Took Part

The abstract describes 66 children taking part.

The age groups tagged for this paper are young children, both men and women.

In this prospective, randomized study, the effects of magnesium supplementation during general anaesthesia on emergence delirium and postoperative pain in children were evaluated.

A total of 66 children aged 2 to 5 years who underwent strabismus surgery were assigned to the magnesium or to the control group.

How the Study Was Run

In design terms this was a randomized study.

The children were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Preoperative anxiety was assessed using the modified Yale Preoperative Anxiety Scale.

The control group received an equal volume of normal saline via the same regimen.

The Paediatric Anaesthesia Emergence Delirium (PAED) score, pain score, and respiratory events were assessed at the postanaesthetic care unit.

What Was Measured

PubMed files the paper under topics including Dietary Supplements, Emergence Delirium, Intraoperative Care, Magnesium, Postoperative Pain, Republic of Korea and Strabismus.

The authors tagged it with the keywords Ophthalmologic surgical procedure and Paediatrics.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 66 children.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2020 (BMC anesthesiology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.