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Association of serum 25-Hydroxyvitamin D with Vitamin D intervention and outdoor activity among children in North China: an observational study.
Plain-language guide to PMID 33267851 (2020): observational study of Vitamin D, K2, Magnesium and Zinc in 55,925 children.
Key Facts
- PMID
- 33267851
- Journal
- BMC pediatrics
- Year
- 2020
- Study type
- Observational Study
- Authors
- Zhang X et al. (9 authors)
- DOI
- 10.1186/s12887-020-02435-9
What This Study Did, in Plain Language
What Was Tested
This observational study looks at Vitamin D, K2, Magnesium and Zinc.
Logistic regression analysis was performed to assess the association of vitamin D intervention or outdoor activity with blood vitamin D status, adjusted for age, gender, BMI for age, and seasons.
Why It Was Studied
Living at high latitudes is one of the risk factors for vitamin D deficiency in children.
This study aims at evaluating the association of different vitamin D intervention methods and outdoor activity on the vitamin D status of children in North China.
Who Took Part
The abstract describes 55,925 children taking part.
By PubMed's age tags, the people studied were children.
In this observational study, a total of 55,925 children aged 1 month to 18 years old were recruited from pediatric outpatient departments from July 2016 to June 2017.
Data on demographics, anthropometric measurements, vitamin D intervention (either prescribed by physicians or given by parents) and outdoor activity were recorded.
How the Study Was Run
The serum levels of 25-hydroxycholecalciferol (25(OH)D) were determined by high performance liquid chromatography tandem-mass spectrometry.
What Was Measured
This study aims at evaluating the association of different vitamin D intervention methods and outdoor activity on the vitamin D status of children in North China.
Topics PubMed links to this paper include Calcifediol, China, Cross-Sectional Studies, Prevalence, Seasons, Vitamin D and Vitamin D Deficiency.
The authors tagged it with the keywords Children, North China, Outdoor activity, Supplementation intervention and Therapeutic intervention.
What This Means in Plain Language
This is an observational study of Vitamin D, K2, Magnesium and Zinc in 55,925 children.
With several hundred people or more, it is a fairly large study for this kind of research.
The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2020 (BMC pediatrics), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.