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Comparison the effect of bupivacaine plus magnesium sulfate with ropivacaine plus magnesium sulfate infiltration on postoperative pain in patients undergoing lumbar laminectomy with general anesthesia.

Plain-language guide to PMID 33332200 (2024): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 60 patients.

Key Facts

PMID
33332200
Journal
British journal of neurosurgery
Year
2024
Study type
Randomized Controlled Trial
Authors
Sane S et al. (5 authors)
DOI
10.1080/02688697.2020.1861430

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

In this study, the researchers investigated the effect of local injection of ropivacaine and bupivacaine with magnesium sulfate on postoperative pain in vertebral laminectomy surgery.

Who Took Part

The study group was 60 patients.

The age groups tagged for this paper are teenagers, young adults, adults, middle-aged adults and older adults.

This randomized double-blind prospective study was conducted among 60 patients aged 18-65 years old with ASA class I and II.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the patients and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

What Was Measured

PubMed files the paper under topics including Bupivacaine, Ropivacaine, Magnesium Sulfate, Anesthetics, Local, Laminectomy, Saline Solution and Postoperative Pain.

The authors tagged it with the keywords lumbar laminectomy.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 60 patients.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2024 (British journal of neurosurgery), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.