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Effects of whey protein plus vitamin D supplementation combined with progressive resistance training on glycaemic control, body composition, muscle function and cardiometabolic risk factors in middle-aged and older overweight/obese adults with type 2 diabetes: A 24-week randomized controlled trial.

Plain-language guide to PMID 33369020 (2021): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
33369020
Journal
Diabetes, obesity & metabolism
Year
2021
Study type
Randomized Controlled Trial
Authors
Miller EG et al. (6 authors)
DOI
10.1111/dom.14299

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

To determine the effect of whey protein plus vitamin D supplementation combined with progressive resistance training (PRT) on glycaemic control, body composition, muscle function and cardiometabolic risk factors in middle-aged and older adults with type 2 diabetes (T2D).

Who Took Part

The age groups tagged for this paper are middle-aged adults and older adults.

Primary outcomes were HbA1c and homeostatic model assessment-2 of insulin resistance (HOMA2-IR).

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Secondary endpoints included fasting plasma glucose (FPG), body composition, muscle strength, physical function, blood pressure, blood lipids and inflammatory markers.

What Was Measured

The subject headings attached to it are Body Composition, Cardiometabolic Risk Factors, Diabetes Mellitus, Type 2, Dietary Supplements, Glycemic Control, Muscles and Obesity.

Author keywords: body composition, clinical trial, dietary intervention, exercise intervention, randomized trial, type 2 diabetes.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2021 (Diabetes, obesity & metabolism), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.