Role of vitamin D-calcium supplementation on metabolic profile and oxidative stress in gestational diabetes mellitus: A randomized controlled trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

To assess role of vitamin D-calcium supplementation on the metabolic profile and oxidative stress in women with Gestational Diabetes Mellitus (GDM) controlled on diet.

Who Took Part

PubMed tags the participants as women only.

Levels of serum 25-hydroxy vitamin D, fasting plasma glucose (FPG), serum insulin, fasting lipid profile and total glutathione (GSH) were analyzed both prior to and after supplementation.

How the Study Was Run

In design terms this was a randomized and double-blind study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

A randomized controlled trial was conducted at a tertiary care teaching hospital.

Means, standard deviations and mean change were computed.

What Was Measured

The subject headings attached to it are Blood Glucose, Calcium, Diabetes, Gestational, Dietary Supplements, Insulin, Metabolome and Oxidative Stress.

Author keywords: gestational diabetes mellitus, glucose metabolism and vitamin D.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2021 (The journal of obstetrics and gynaecology research), a journal based in Australia.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.