Changes in Ghrelin and Glucagon following a Low Glycemic Load Diet in Women with PCOS

What Was Tested

Researchers studied Glucagon and Ghrelin in the context of pcos in this randomized controlled trial publication.

At each diet midpoint, a solid meal test was administered to examine postprandial ghrelin, glucagon, glucose, insulin, and self-reported appetite scores.

Why It Was Studied

Altered satiety hormones in women with polycystic ovarian syndrome (PCOS) may contribute to obesity.

Diets with a low glycemic load (GL) may influence appetite-regulating hormones including glucagon and ghrelin.

Who Took Part

The age groups tagged for this paper are young adults, adults and middle-aged adults, women only.

Thirty women diagnosed with PCOS.

How the Study Was Run

In design terms this was a randomized and crossover study.

The participants were allocated by chance, so the Glucagon group and the comparison group should start out alike.

In the crossover set-up each of the participants took both Glucagon and the comparison in turn, acting as their own control.

Secondary analysis of a randomized crossover trial.

What Was Measured

Topics PubMed links to this paper include Diet, Energy Intake, Ghrelin, Glucagon, Glycemic Load, Hunger and Polycystic Ovary Syndrome.

Author keywords: appetite and satiety.

What This Means in Plain Language

The paper is a randomized and crossover study of Glucagon and Ghrelin in people with pcos.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2021 (The Journal of clinical endocrinology and metabolism), a journal based in United States.

More context: the Glucagon compound page and the Ghrelin compound page, PCOS research.