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Effect of Vitamin D Supplementation in Early Life on Children's Growth and Body Composition: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Plain-language guide to PMID 33562750 (2021): meta-analysis of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 33562750
- Journal
- Nutrients
- Year
- 2021
- Study type
- Meta-Analysis
- Authors
- Ma K et al. (5 authors)
- DOI
- 10.3390/nu13020524
What This Paper Covers, in Plain Language
What It Covers
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a meta-analysis.
The researchers aim to summarize the available evidence on the effect of vitamin D supplementation in pregnancy and infancy on child growth and body composition.
Why It Was Studied
No systematic review has been conducted to summarize available evidence on the effect of vitamin D supplementation in pregnancy and infancy on growth and body composition in children.
Who the Included Studies Covered
PubMed indexes the participants as infants, women only.
A systematic review and meta-analysis were performed on the effects of vitamin D supplementation during early life on children's growth and body composition (bone, lean and fat).
A literature search of randomized controlled trials (RCTs) was conducted to identify relevant studies on the effects of vitamin D supplementation during pregnancy and infancy on children's body composition (bone, lean and fat) in PubMed, EMBASE and Cochrane Library from inception to 31 December 2020.
How the Review Was Done
A Cochrane Risk Assessment Tool was used for quality assessment.
The comparison was vitamin D supplementation vs. placebo or standard care.
Random-effects and fixed-effect meta-analyses were conducted.
What Was Measured
PubMed files the paper under topics including Adiposity, Bias, Body Composition, Body Height, Body Mass Index, Bone Density and Confidence Intervals.
The authors tagged it with the keywords Vitamin D, childhood, infancy, pregnancy and randomized controlled trials.
What This Means in Plain Language
This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.
Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2021 (Nutrients), a journal based in Switzerland.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.